In the event of corruption of the Microsoft Windows registry, system files, or the System Center Data Protection Manager (DPM) 2010 binaries, you can repair DPM by reinstalling it. Repairing DPM involves backing up existing DPM database (using DPMBackup.exe -db cmd), uninstalling DPM, reinstalling DPM and then restoring the database. See this technet article for step-by-step.